Missouri vs. LSU: How to watch, schedule, live stream info, game time, TV channel How to watch Missouri vs. LSU football game. Who's Playing No. 1 LSU @ Missouri Current Records: LSU 1-1; Missouri 0-2 What to Know The LSU Tigers are on the road again on Saturday and play against the Missouri Tigers at noon ET Oct. 10 at Memorial Stadium at Faurot Field. LSU won't have the home-field advantage, but they do enjoy a 20.5-point advantage in the spread. You can't lose the game if you win every quarter, and that was precisely LSU's strategy against the Vanderbilt Commodores last week. LSU took their contest against Vanderbilt by a conclusive 41-7 score. The matchup was all but wrapped up at the end of the third, by which point LSU had established a 34-7 advantage. LSU QB Myles Brennan was slinging it as he passed for four TDs and 337 yards on 37 attempts. Near the top of the highlight reel was Brennan's 51-yard TD bomb to WR Terrace Marshall Jr. in the second quarter. Meanwhile, a victory for Mizzou just wasn't in the stars last week as the team never even grasped a temporary lead. Their painful 35-12 loss to the Tennessee Volunteers might stick with them for a while. Mizzou was surely aware of their 10.5-point disadvantage in the point spread, but the foreknowledge did nothing to prevent the result. QB Connor Bazelak had a pretty forgettable game, throwing one interception. LSU is the favorite in this one, with an expected 20.5-point margin of victory. Those taking them against the spread are banking on an outcome similar to that of the team's matchup last week, where they covered a 21-point spread. LSU's win lifted them to 1-1 while Missouri's defeat dropped them down to 0-2. We'll see if LSU can repeat their recent success or if Mizzou bounces back and reverse their fortune. How To Watch When: Saturday at 12 p.m. ET Where: Memorial Stadium at Faurot Field -- Columbia, Missouri Online streaming: WatchESPN Follow: CBS Sports App Odds The Tigers are a big 20.5-point favorite against the Tigers, according to the latest college football odds. Over/Under: -110 See college football picks for every single game, including this one, from SportsLine's advanced computer model. Get picks now.